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Can isoniazid cause liver damage? Due to its high efficacy, isoniazid (INH) remains the drug of choice for treatment of latent tuberculosis (TB) despite the fact that it can cause liver failure 1. Severe liver injury is seen in up to 1% of the patients 2, 4.
Does Rifampin cause heartburn? This drug may cause upset stomach, heartburn, nausea, menstrual changes, headache, drowsiness, or dizziness. Rifampin may rarely cause serious liver disease. Though sometimes necessary to completely treat certain infections, combination treatment with other drugs (e.g., isoniazid, pyrazinamide) may increase this risk.
Which TB drug causes orange urine? Rifampicin
Can I drink beer after TB treatment? Tell your TB doctor about any other medications you are taking. Ensure you take the medication long enough to kill all of the tuberculosis bacteria – a minimum of six months. Avoid drinking alcohol while on tuberculosis treatment. Alcohol can increase drug side effects and toxicity, because both can affect the liver.
How long does rifampin stay in the body? In healthy adults, the mean biological half-life of rifampin in serum averages 3.35± 0.66 hours after a 600 mg oral dose, with increases up to 5.08± 2.45 hours reported after a 900 mg dose. With repeated administration, the half-life decreases and reaches average values of approximately 2 to 3 hours.
Where is leprosy found? Leprosy can affect people of all races all around the world. However, it is most common in warm, wet areas in the tropics and subtropics. Worldwide prevalence is reported to be around 5.5 million, with 80% of these cases found in 5 countries: India, Indonesia, Myanmar, Brazil and Nigeria.
Can leprosy be transmitted from mother to child? She was discharged with the baby on postoperative day 3. Leprosy is a chronic disease caused by Mycobacterium leprae. The infant has a potentially high risk of contracting leprosy from the mother by skin-to-skin contact or droplet transmission, particularly if she has not received treatment.
WHO Leprosy guidelines? The guidelines recommend a 3-drug regimen of rifampicin, dapsone and clofazimine for all leprosy patients, with a duration of treatment of 6 months for PB leprosy and 12 months for MB leprosy.
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